Publications

Wound Healing Assay
Related ECIS Publications

Saxena, N.K., Sharma, D., Ding, X. Lin, S., Marra, F., Merline, D. Anania, F., "Concomitant Activation of the JAK/STAT, P13K/AKT and ERK Signaling is Involved in Leptin-Mediated Promotion of Invasion and Migration of Hepatocellular Carcinoma Cells." [PDF] Cancer Research: 2497-2507 (2007).

Earley, S., Plopper, G.E., "Disruption of focal adhesion slows transendothelial migration of AU-565 breast cancer cells." Biochemical and Biophysical Research Communications: 405-412 (2006).

Sapper, A., Wegener, J., Janshoff, A., "Cell motility probed by noise analysis of thickness shear mode resonators." Anal Chem. 15;78(14):5184-91, (2006).

Ren, J., Xiao, Y., Singh, L.S., Zhao, X., Zhao, Z., Feng, L., Rose, T.M., Prestwich, G.D., Xu, Y.,"Lysophosphatidic Acid Is Constitutively Produced by Human Peritoneal Mesothelial Cells and Enhances Adhesion, Migration, and Invasion of Ovarian Cancer Cells." [PDF] Cancer Res 2006; 66: (6) (2006).

Waters, C.M., Long, J., Gorshkova, I., Fujiwara, Y., Connell, M., Belmonte, K.E., Tigyi, G., Natarajan, V., Pyne, S., Pyne, N.J., "Cell migration activated by platelet-derived growth factor receptor is blocked by an inverse agonist of the sphingosine 1-phosphate receptor-1." The FASEB Journal Express Article 10.1096/fj.05-4810fje (2005).

Charrier, L., Yan, Y., Driss, A., Laboisse, C.L., Sitaraman, S.V. and Merlin, D.,"ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers." AJP Gastrointest Liver Physiol. 288:346-353, (2005).

Kucharzik, T., Lugering, A., Yan, Y., Driss, A., Charrier, L., Sitaraman, S., Merlin, D., "Activation of epithelial CD98 glycoprotein perpetuates colonic inflammantion", Laboratory Investigation 1-10 (2005)

Charrier, L., Yan, Y., Driss, A., Laboisse, C.L., Sitaraman, S.V., Merlin, D. "ADAM-15 Inhibits Wound Healing in Human Intestinal Epithelial Cell Monolayers." Am J Physiol Gastrointest Liver Physiol. [Epub ahead of print] (2004).

Keese, Charles R., Wegener, Joachim, Walker, Sarah R., and Giaever, Ivar. "Electrical Wound-healing assay for cell in vitro". [PDF] PNAS 101: 1554-1559 (2004). Download pdf file

Hug, T.S. "Biophysical methods for monitoring cell-substrate interactions in drug discovery." Assay Drug Dev Technol. 1(3):479-88. (2003).

Lundien, M.C., Mohammed, K.A., Nasreen, N., Tepper, R.S., Hardwick, J.A., Sanders, K.L., Van Horn, R.D., Antony, V.B. "Induction of MCP-1 expression in airway epithelial cells: role of CCR2 receptor in airway epithelial injury." J Clin Immunol. 22(3):144-52 (2002).

Wegener, J., Keese, C.R., Giaever, I, "Recovery of Adherent Cells After In Situ Electroporation Monitored Electronically" Bio Techniques 33(2), 348ff (2002)

Hadjout, N., Laevsky, G., Knecht, D.A., Lynes ,M.A., "Automated real-time measurement of chemotactic cell motility", Biotechniques, 31 (5): 1130-1138 (2001).

Lo, C.M., Linton, M., Keese, C.R., Giaever, I. "Correlated motion and oscillation of neighboring cells in vitro." Cell Commun Adhes. 8(3):139-45 (2001).

Burns, A.R., R.A. Bowden, S.D. MacDonell, D.C. Walker, T.O. Odebunmi, E.M. Donnachie, S.I. Simon, M.L. Entman, and C.W. Smith. "Analysis of Tight Junctions During Neutrophil Transendothelial Migration", J. of Cell Sci, 113:45-75. (2000)

Huang, C.N., Lo, C.M., Hsu, T.C., Tsay, G.J. "Sera from patients with scleroderma inhibit fibroblast micromotions monitored electrically." J Rheumatol. 26(6):1312-7 (1999).

Noiri, E., Lee, E., Testa, J., Quigley, J., Colflesh, D., Keese, C., Giaever, I. and Goligorsky, M., "Podokinesis in endothelial cell migration: role of nitric oxice", Am. J. Physiol. 43, 236C (1998).

Moy A.B., Van Engelenhoven,J., Bodmer, J., Kamath, J., Keese, C.,Giaever, I., Shasby,S., and Shasby, D.M., "Histamine and Thrombin Modulate Endothelial Focal Adhesion Through Centripetal and Centrifugal Forces",J Clin. Inv. (1996)

Burns, A., Walker, D., Brown, E., Thurmon, L., Bowden, R., Keese, C., Simon, S., Entman, M.and Smith, W., "Neutrophil Transendothelial Migration Is Independent of Tight Junctions and Occurs Preferentially at Tricellular Corners", J. of Immunol. 22, 2893-2903 (1997).st. 97, 1020-1027 (1996).

Lo, C.M., Keese, C.R., Giaever, I. "Monitoring motion of confluent cells in tissue culture." Exp Cell Res. 204(1):102-9 (1993).